1.Which of the following Calcium-channel blockers preferred in the treatment of subarachnoid hemorrhage?
a.Amlodipine
b.Nifedipine
c.Nimodipine
d.Felodipine
e.Verapamil
2.This sulfonylurea is preferred for the elderly because of its shorter half-life
a.Tolbutamide
b.Glipizide
c.Glimepiride
d.Gliclazide
e.Glibenclamide
3.This drug acts by inhibiting activity of dipeptidyl-peptidase 4 (DPP4i)
a. Metformin
b.Pioglitazone
c.Vildagliptin
d.Glimepiride
e.Mixtard
4.This type of insulin is essential in the acute management of hyperglycemia
a. Soluble human insulin
b.Insulin glargine
c.Insulin detemir
d.Neutral Protamine Hagedorn
e.Mixtard
5.The following drugs cause hypoglycemiaEXCEPT
a.Ethanol
b.Haloperidol
c.Bendroflumethiazide
d.Quinine
e.Glimepiride
6.Active management of adult hypoglycemia involves the infusion of
a.50 mls of 50% Dextrose
b.100 mls of 10% Dextrose
c.500 mls of Ringers lactate d.
d.10IU of Soluble insulin
e.100 mls Of Dextrose in Normal saline
7.The following are used in the management of hyperthyroidism EXCEPT
a.Carbimazole
b.Propylthiouracil
c.Propranolol
d.Radio-Iodine
e.Thiopental
8.Management of thyroid storm involves the use of all the following EXCEPT
a.Hydrocortisone
b.Levo-thyroxine
c.Propranolol
d.Supplemental oxygen
e.Propylthiouracil
9.Which of the following antihypertensives is likely to precipitate hyperuricemia and
hyperlipidemia?
a. Hydrochlorothiazide
b. Spironolactone
c. Amlodipine
d. Labetalol
e. Methyldopa
10.All the following are beneficial in acute heart failure, except
a. Furosemide
b. Morphine
c. Digoxin
d. Dobutamine
e. carvedilol
11.Which treatment would be appropriate for a patient with scabies?
a. Benzyl benzoate
b. Erythromycin
c. Fluconazole-
d. Ketoconazole 2% shampoo
c. Tetracycline
12.The use of isoniazid is associated with
a. Thrombocytopenia
b. Polyneuropathy
c. Ototoxicity
d. Optic neuritis
e. hyperurecemia
13.This drug may cause efferent glomerular arteriolar dilatation with consequent depression of giomerular filtration pressure
a.Lisinopril
b.Bendroflumethiazide
c.Furosemide
d.Amlodipine
e.Carvedilol
14. In hyperkalemia, this is essential in pretecting the myocardium
a.Calcium gluconate
b.Potassium chloride
c.Anti-potassium citrate
d.Lugol iodine
e.Insulin glargine
15.This drug is beneficial in the management of CKD when there is proteinuria
a.Losartan
b.Amlodipine
c.Bendroflumethiazide
d.Spironolactone
e.Methyldopa
16.This drug is the first line in the management of minimal change nephropathy
a.Cyclosporine
b.Azathioprine
c.Prednisolone
d.Methotrexate
e.Cyclophosphamide
17.Disease modifying anti-rheumatic drugs needed in the management of rheumatoid arthritis includes the following EXCEPT
a.Sulfasalazine
b.Methotrexate
c.Methylprednisolone
d.Leflunomide
e.Rituximab
18.Side effects of Metformin includes the following EXCEPT
a.Anorexia
b.Epigastric discomfort
c.Hypoglycemia
d.Diarrhea
e.Lactic acidosis
19.Which of the following drugs is most likely to cause systemic lupus-like syndrome?
a.Baclofen
b.Isoniazid
c.Methotrexate
d.Procainamide
e.Sulfasalazine
20.The first line antihypertensive medication in the general black population is
a. Angiotensin-Converting Enzyme inhibitor
b. Angiotensin receptor blockers
c. Thiazide diuretics
d. Loop diuretics
e. Beta blockers
21.Which of the following is wrongly matched with its compelling indication?
a. Left ventricular hypertrophy – Angiotensin-Converting enzyme inhibitors, Angiotensin receptor blockers, calcium channel blockers
b.Microalbuminuria – Angiotensin-Converting enzyme inhibitors or Angiotensin receptor blockers
c. Renal dysfunction – Thiazide diuretics
d. Coronary artery disease – Angiotensin-Converting enzyme inhibitors, Angiotensin receptor blockers, Beta blockers, Calcium channel blockers
e.Diabetes mellitus – Angiotensin-Converting enzyme inhibitors or Angiotensin receptor blockers
22.Compelling contraindications for antihypertensive medicines include the following except
a. Gout – thiazide diuretics
b. Asthma – beta blockers
c. Congestive cardiac failure – loop diuretics
d.Hyperkalaemia Angiotensin-Converting enzyme inhibitors and Angiotensin receptor blockers
e. Bilateral renal artery stenosis – Angiotensin-Converting enzyme inhibitors or Angiotensin receptor blockers
23Which of the following antihypertensive medications is best recommended for a patient with atrial fibrillation?
a. Thiazide diuretics
b. Loop diuretic.s
c. Angiotensin receptor blockers
d. Calcium channel blockers
e. All of the above
24.For coronary artery disease, which of these antihypertensive medications is most recommended?
a. Thiazide diuretics
b. Loop diuretics
c. Potassium sparing diuretics
d. Calcium channel blockers
e. Angiotensin converting enzyme inhibitor
25.The most preferred antihypertensive medicine in the management of stroke is
a. Thiazide diuretics
b. Loop diuretics
c. Potassium sparing diuretics
d. Calcium channel blockers
e.Angiotensin converting enzyme inhibitor
26.Hypertensive patient with microalbuminuria should be managed with
a. Thiazide diuretics
b. Loop diuretics
c.Angiotensin converting enzyme inhibitor
d. Potassium sparing diuretics
e. Calcium channel blockers
27.A hypertensive patient with left ventricular hypertrophy should be put on
a. Thiazide diuretics
b. Loop diuretics
c. Angiotensin converting enzyme inhibitor
d. Potassium sparing diuretics
e. Calcium channel blockers
28.Which of the following medications is most contraindicated in the management of heart failure?
a. Angiotensin receptor blockers
b. Loop diuretics
c.Angiotensin converting enzyme inhibitor
d. Potassium sparing diuretics
e. Calcium channel blockers
29.Hypertensive patients with gouty arthritis should not be put on
a. Thiazide diuretics
b. Loop diuretics
c. Angiotensin converting enzyme inhibitor
d. Potassium sparing diuretics
e. Calcium channel blockers
30.In managing hypertension, which of the following medications should be avoided in hypercalcemia?
a. Thiazide diuretics
b. Loop diuretics
c.Angiotensin converting enzyme inhibitor
d. Beta blockers
e. Calcium channel blockers
31.A hypertensive patient with known or suspected bilateral renal artery stenosis should not be put on
a. Thiazide diuretics
b. Loop diuretics
c.Angiotensin converting enzyme inhibitor
d. Potassium sparing diuretics
e. Calcium channel blockers
32.Which of the following medications is used as first line treatment in acute moderate exacerbation of asthma?
a. Hydrocortisone
b. Aminophylline
c. Salbutamol
d. Prednisolone
e. Montelukast
33.All are medicines used in the management of chronic asthma except
a. Salbutamol
b. Prednisolone
c. Aminophylline
d. Montelukast
e. Budesonide
34. All of the following agents are used for prophylaxis of migraine except-
a.Propanolol
b.Valproate
c.Topiramate
d.Ethosuximide
35.Which of the following drugs is a first-line treatment for uncomplicated malaria caused by Plasmodium falciparum?
a. Chloroquine
b. Quinine
c. Mefloquine
d. Artemether-lumefantrine
e. Doxycycline
36.The medication of choice for treatment of acute gout attack is
a. Colchicine
b. Allopurinol
c. Febuxostat
d. Probenecid
e. Methotrexate
37.Which of the following drugs is NOT a first-line treatment for status epilepticus?
a. Diazepam
b. Lorazepam
c. Phenytoin
d. Levetiracetam
e. Carbamazepine
38.The following medication is contraindicated in patients with severe hepatic impairment
a. Metformin
b. Sitagliptin
c. Pioglitazone
d. Acarbose
e. Glipizide
39.Which of the following drugs is a preferred treatment option for patients with moderate to severe chronic obstructive pulmonary disease (COPD)?
a. Albuterol
b. Tiotropium
c. Montelukast
d. Fluticasone-salmeterol
e. Theophylline
40.The drug of choice for the first-line treatment of hypertension in patients with diabetes is
a. Atenolol
b. Lisinopril
c. Nifedipine
d. Spironolactone
e. Verapamil
SUGGESTED SOLUTION
- C 11.A 21.C 31.C
- A 12.B 22.E 32.C
- A 13.C 23.D 33.B
- A 14.A 24 E 34 D
- B 15.A 25.E 35.D
- B 16.C 26.C 36.A
- E 17.C 27.C 37.E
- B 18.C 28.E 38.C
- A 19.D 29.A 39.D
- E 20.C 30.A 40.B